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KMID : 0363220090470040459
Korean Journal of Dermatology
2009 Volume.47 No. 4 p.459 ~ p.462
A Case of Nicolau Syndrome Treated with Non-steroidal Anti-inflammatory Drug Injection Therapy
Chang Hee-Sun

Moon Hyung-Sik
Lee Hyun-Kyung
Park Kun
Son Sook-Ja
Abstract
Nicolau syndrome, also known as livedoid dermatitis or embolia cutis medicamentosa, is a rare cutaneous adverse drug reaction characterized by the acute onset of cutaneous and soft-tissue necrosis following intramuscular drug injection. The typical presentation is pain around the injection site, developing into erythema, a livedoid patch, and necrosis of the skin, subcutaneous fat, and muscle tissue. We report a 72-year-old man who presented with a painful, erythematous patch on his left buttock. The patient was treated with non-steroidal anti-inflammatory drug (diclofenac sodium) injection.
KEYWORD
Diclofenac sodium, Nicolau syndrome, Non-steroidal anti-inflammatory drug
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